+86-400-828-8830 +86-181-1292-4986 info@biointron.com

Antibody Humanization Service

 

Antibody humanization is used for reducing the immunogenicity of animal monoclonal antibodies and for promoting their activities in the human immune system. It is critical to therapeutic antibody discovery.


 Antibody Humanization Service 

Biointron

Biointron offers reliable CDR transplantation-based antibody humanization services. Biointron has established a highly efficient process for alpaca antibody humanization. We deliver humanized antibodies which retain full binding affinity and specificity as their parental antibodies. Our final humanized antibody will have optimized expression levels without any undesired residues in their CDR or framework (FR). In addition, several humanized therapeutic antibody drugs designed by our experts have entered the clinical stage.


Service Features 

Biointron
01

Chimeric control antibody

02

Consistency of affinity of humanized antibody and chimeric antibody

03

Derived from a variety of species 

04

Sequences can come from a variety of forms

05

Antibody polymer analysis based on SEC-HPLC 

06
      Guaranteed affinity based on Biacore T200 
07

Proprietary high-throughput rapid expression platform


Case Study

Biointron


Humanized antibody variant expression yields relative to the original chimeric antibody

Model for antibody-antigen interface



info@biointron.com

+86-400-828-8830 +86-181-1292-4986